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John PCunhaDOis a U.Sboard-certified Emergency Medicine PhysicianDrCunha’s educational background includes a BS in Biology from Rutgersthe State University of New Jerseyand a DO from the Kansas City University of Medicine and Biosciences in Kansas CityMOHe completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in NewarkNew Jersey.
In the United Statesthe labeling of letrozole already warned that it had been associated with birth defectsNovartis has never sought FDA approval to market letrozole as a fertility medication and was clearly concerned about their liability if given in pregnancy.
It is not known whether letrozole passes into breast milk or if it could harm a nursing babyYou should not breast-feed while you are using Femara and for at least 3 weeks after your last dose.
In postmenopausal womenAdjuvant treatment of hormone receptor positive early breast cancerExtended adjuvant treatment of early breast cancer after 5 years of adjuvant tamoxifen therapyFirst-line treatment of hormone receptor positive or unknownlocally advanced or metastatic breast cancerTreatment of advanced breast cancer with disease progression following antiestrogen therapy.
For use as extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy2.5 mg tablet orally administered once a day without regard to meals.
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femara and arimidex represent the newest achievements in a long line of drugs targeting aromatase inhibition.